記憶分子光解析センター

重点リサーチセンター

記憶分子光解析センター

Optical Neurobiology Center

活動実績

  1. （1）Shidara H, Jitsuki S, Takemoto K. Chromophore-assisted light inactivation of target proteins for singularity biology. Biophys Physicobiol, 21, e211009, (2024)
  2. （2）Jahan A, Akter TM, Takemoto K, Oura T, Shitara A, Semba S, Nezu A, Suto S, Nagai T, Tanimura A Insertion of circularly permuted cyan fluorescent protein into the ligand-binding domain of inositol 1,4,5-trisphosphate receptor for enhanced FRET upon binding of fluorescent ligand. Cell Calcium, 108, (2022)
  3. （3）Takemoto K. Optical manipulation of molecular function by chromophore-assisted light inactivation. Proc Jpn Acad Ser B Phys Biol Sci. 2021;97(4):197-209
  4. （4）Trusel M, Nuno-Perez A, Lecca S, Harada H, Lalive AL, Congiu M, Takemoto K, Takahashi T, Ferraguti F and Manuel M Punishment-predictive cues guide avoidance through potentiation of hypothalamus-to-habenula synapses. Neuron, 102, (2019)
  5. （5）Takemoto K* (*co-corresponding author), Iwanari H, Tada H, Suyama K, Sano A, Nagai T, Hamakubo T and Takahashi T* "Optical inactivation of synaptic AMPA receptors erases fear memory." Nat. Biotechnol., 35(1):38-47, 2017

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